MICHAEL H. FARKAS, PHD
- ROSS EYE INSTITUTE -
Vision Research Center
Specialties
- Vision Research Center
Contact
Building 20, Room 239
Buffalo, NY 14215
Phone:
716-834-9200, ext. 5638
Email: mhfarkas@buffalo.edu
Education
Title and Department:
Assistant Professor, Ophthalmology
Education and Training:
Ph.D. Biological Sciences, University at Buffalo
M.S. Biotechnology, Johns Hopkins University
Clinical Fellowship (Ophthalmology):
Harvard Medical School (2014)
University of Pennsylvania (2011)
Research Focus:
Bioinformatics; eukaryotic pathogenesis; gene expression; gene therapy; genomics and proteomics; molecular and cellular biology; molecular basis of disease; molecular genetics; RNA; stem cells; vision science
Clinical Relevance:
Functional characterization of a novel splice variant in PRPF31, role of RNA splicing factors in retinal degeneration
Research Journal Articles
- Pan J, Liu S, Farkas M, Consugar M, Zack D, Fernando Arevalo J, Pierce E, Qian J, Al Kahtani E. Identification of serum biomarker for proliferative diabetic retinopathy. Molecular Vision. 2016.
- Farkas MH, Au ED, Sousa ME, Pierce EA. RNA-Seq: Improving Our Understanding of Retinal Biology and Disease. Cold Spring Harb Perspect Med. 2015; 5(9).
- Bujakowska KM, Consugar M, Place E, Harper S, Lena J, Taub DG, White J, Navarro-Gomez D, Weigel DiFranco C, Farkas MH, Gai X, Berson EL, Pierce EA. Targeted exon sequencing in Usher syndrome type I. Invest Ophthalmol Vis Sci. 2014; 55(12).
- Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF. Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium. Am J Pathol. 2014; 184(10).
- Farkas MH, Grant GR, White JA, Sousa ME, Consugar MB, Pierce EA. Transcriptome analyses of the human retina identify unprecedented transcript diversity and 3.5 Mb of novel transcribed sequence via significant alternative splicing and novel genes. BMC Genomics. 2013; 14.
- Farkas MH, Grant GR, Pierce EA. Transcriptome analyses to investigate the pathogenesis of RNA splicing factor retinitis pigmentosa. Adv Exp Med Biol. 2012; 723.
- Grant GR, Farkas MH, Pizarro AD, Lahens NF, Schug J, Brunk BP, Stoeckert CJ, Hogenesch JB, Pierce EA. Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM). Bioinformatics. 2011; 27(18).
- Graziotto JJ, Farkas MH, Bujakowska K, Deramaudt BM, Zhang Q, Nandrot EF, Inglehearn CF, Bhattacharya SS, Pierce EA. Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration. Invest Ophthalmol Vis Sci. 2011; 52(1).
- Farkas MH, Mojica ER, Patel M, Aga DS, Berry JO. Development of a rapid biolistic assay to determine changes in relative levels of intracellular calcium in leaves following tetracycline uptake by pinto bean plants. Analyst. 2009; 134(8).
- Farkas MH, Berry JO, Aga DS. Chlortetracycline detoxification in maize via induction of glutathione S-transferases after antibiotic exposure. Environ Sci Technol. 2007; 41(4).
- Farkas MH, Berry JO, Aga DS. Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography/mass spectrometry. Analyst. 2007; 132(7).
- Perez S, Farkas MH, Barcelo D, Aga DS. Characterization of glutathione conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. Rapid Communications in Mass Spectrometry. 2007; 21(24).
